Differential microRNA regulation correlates with alternative polyadenylation pattern between breast cancer and normal cells.
Alternative polyadenylation (APA) could result in mRNA isoforms with variable lengths of 3' UTRs. Gain of microRNA target sites in the 3' UTR of a long mRNA isoform may cause different regulation from the corresponding short isoform. It has been known that cancer cells globally exhibit a l...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23437281/pdf/?tool=EBI |