Setting the Beta-Lactam Therapeutic Range for Critically Ill Patients: Is There a Floor or Even a Ceiling?

OBJECTIVES:. Beta-lactam antibiotics exhibit high interindividual variability in drug concentrations in patients with critical illness which led to an interest in the use of therapeutic drug monitoring to improve effectiveness and safety. To implement therapeutic drug monitoring, it is necessary to...

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Bibliographic Details
Main Authors: Erin F. Barreto, PharmD, MSc, Andrew J. Webb, PharmD, Gwendolyn M. Pais, PhD, Andrew D. Rule, MD, Paul J. Jannetto, PhD, Marc H. Scheetz, PharmD, MSc
Format: Article
Language:English
Published: Wolters Kluwer 2021-06-01
Series:Critical Care Explorations
Online Access:http://journals.lww.com/10.1097/CCE.0000000000000446