The enigma of soluble LDLR: could inflammation be the key?

Abstract Soluble low-density lipoprotein receptor (sLDLR) is the circulating ectodomain of transmembrane LDLR. Its blood level strongly correlates with that of triglycerides (TG). This correlation has eluded satisfactory explanation. Hypertriglyceridemia and shedding of the ectodomain of many transm...

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Bibliographic Details
Main Authors: Majambu Mbikay, Janice Mayne, Michel Chrétien
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Lipids in Health and Disease
Subjects:
Online Access:https://doi.org/10.1186/s12944-020-1199-9