Computational intractability law molds the topology of biological networks

Abstract Virtually all molecular interaction networks (MINs), irrespective of organism or physiological context, have a majority of loosely-connected ‘leaf’ genes interacting with at most 1-3 genes, and a minority of highly-connected ‘hub’ genes interacting with at least 10 or more other genes. Prev...

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Bibliographic Details
Main Authors: Ali A. Atiia, Corbin Hopper, Katsumi Inoue, Silvia Vidal, Jérôme Waldispühl
Format: Article
Language:English
Published: SpringerOpen 2020-06-01
Series:Applied Network Science
Subjects:
Online Access:http://link.springer.com/article/10.1007/s41109-020-00268-0