Intricate and Cell Type-Specific Populations of Endogenous Circular DNA (eccDNA) in Caenorhabditis elegans and Homo sapiens

Intricate and Cell Type-Specific Populations of Endogenous Circular DNA (eccDNA) in Caenorhabditis elegans and Homo sapiens

Investigations aimed at defining the 3D configuration of eukaryotic chromosomes have consistently encountered an endogenous population of chromosome-derived circular genomic DNA, referred to as extrachromosomal circular DNA (eccDNA). While the production, distribution, and activities of eccDNAs rema...

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Bibliographic Details
Main Authors: Massa J. Shoura, Idan Gabdank, Loren Hansen, Jason Merker, Jason Gotlib, Stephen D. Levene, Andrew Z. Fire
Format: Article
Language:English
Published: Oxford University Press 2017-10-01
Series:G3: Genes, Genomes, Genetics
Subjects:
C. elegans
circular DNAs
eccDNA
3D genome architecture
circulome
mucin
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.300141

Internet

http://g3journal.org/lookup/doi/10.1534/g3.117.300141

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