Discovery of immunogenic cell death-inducing ruthenium-based photosensitizers for anticancer photodynamic therapy

Discovery of immunogenic cell death-inducing ruthenium-based photosensitizers for anticancer photodynamic therapy

We report a new class of ruthenium (Ru)-based photosensitizers that induce potent cytotoxicity in melanoma cells following activation with NIR light. In addition to the direct cytotoxic effect, this Ru-based photodynamic therapy induces immunogenic cell death in melanoma cells that can be therapeuti...

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Bibliographic Details
Main Authors: Prathyusha Konda, Liubov M. Lifshits, John A. Roque, Houston D. Cole, Colin G. Cameron, Sherri A. McFarland, Shashi Gujar
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
photosensitizer
photodynamic therapy
immunogenic cell death
antitumor immunity
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1863626

Internet

http://dx.doi.org/10.1080/2162402X.2020.1863626

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