Network Architecture and Mutational Sensitivity of the C. elegans Metabolome

A fundamental issue in evolutionary systems biology is understanding the relationship between the topological architecture of a biological network, such as a metabolic network, and the evolution of the network. The rate at which an element in a metabolic network accumulates genetic variation via new...

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Bibliographic Details
Main Authors: Lindsay M. Johnson, Luke M. Chandler, Sarah K. Davies, Charles F. Baer
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2018.00069/full