Putative positive role of inflammatory genes in fat deposition supported by altered gene expression in purified human adipocytes and preadipocytes from lean and obese adipose tissues

Abstract Background Obesity is a chronic low-grade inflammatory disease that is generally characterized by enhanced inflammation in obese adipose tissue (AT). Here, we investigated alterations in gene expression between lean and obese conditions using mRNA-Seq data derived from human purified adipoc...

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Bibliographic Details
Main Authors: Sang-Hyeop Lee, Nak-Hyeon Choi, In-Uk Koh, Bong-Jo Kim, Song Lee, Song-Cheol Kim, Sun Shim Choi
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Journal of Translational Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12967-020-02611-6