Prenatal hyperandrogenization induces metabolic and endocrine alterations which depend on the levels of testosterone exposure.

Prenatal hyperandrogenism is able to induce polycystic ovary syndrome (PCOS) in rats. The aim of the present study was to establish if the levels of prenatal testosterone may determine the extent of metabolic and endocrine alterations during the adult life. Pregnant Sprague Dawley rats were prenatal...

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Bibliographic Details
Main Authors: Sabrina Amalfi, Leandro Martín Velez, María Florencia Heber, Susana Vighi, Silvana Rocío Ferreira, Adriana Vega Orozco, Omar Pignataro, Alicia Beatriz Motta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3360026?pdf=render