Indoleamine 2,3-dioxygenase (IDO): Only an enzyme or a checkpoint controller?
Tryptophan (Trp) is one of the important essential amino acids and Kynurenine pathway (KP) is the first and rate limiting step of degrading Trp to active metabolites. Recent studies showed that KP metabolites have antimicrobial and immunosuppressive roles. The main controller enzyme of this pathway...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Turkiye Klinikleri
2017-07-01
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| Series: | Journal of Oncological Sciences |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452336417300201 |