Involvement of dynamin-related protein 1 in free fatty acid-induced INS-1-derived cell apoptosis.

Involvement of dynamin-related protein 1 in free fatty acid-induced INS-1-derived cell apoptosis.

Elevated extracellular free fatty acids (FFAs) can induce pancreatic beta cell apoptosis, thereby contributing to the pathogenesis of type 2 diabetes mellitus (T2D). Mitochondrial dysfunction has been implicated in FFA-induced beta cell apoptosis. However, molecular mechanisms linking mitochondrial...

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Bibliographic Details
Main Authors: Liang Peng, Xiuli Men, Wenjian Zhang, Haiyan Wang, Shiqing Xu, Qing Fang, Honglin Liu, Wenying Yang, Jinning Lou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23166623/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23166623/pdf/?tool=EBI

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