Synergistic Upregulation of Target Genes by TET1 and VP64 in the dCas9–SunTag Platform

Overexpression of a gene of interest is a general approach used in both basic research and therapeutic applications. However, the conventional approach involving overexpression of exogenous genes has difficulty achieving complete genome coverage, and is also limited by the cloning capacity of viral...

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Bibliographic Details
Main Authors: Sumiyo Morita, Takuro Horii, Mika Kimura, Izuho Hatada
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/5/1574