A <it>Poisson </it>mixture model to identify changes in RNA polymerase II binding quantity using high-throughput sequencing technology

<p>Abstract</p> <p>We present a mixture model-based analysis for identifying differences in the distribution of RNA polymerase II (Pol II) in transcribed regions, measured using ChIP-seq (chromatin immunoprecipitation following massively parallel sequencing technology). The statist...

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Bibliographic Details
Main Authors: Liu Yunlong, Feng Weixing, Wu Jiejun, Nephew Kenneth P, Huang Tim HM, Li Lang
Format: Article
Language:English
Published: BMC 2008-09-01
Series:BMC Genomics