MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording

Fiber optic implantation in deep areas of the rodent’s brain for MRI combined with optogenetics is challenging. Here the authors use an MRI-guided robotic arm as the navigation method for accurate fiber optic placement and precise microinjection during multi-modal fMRI, optogenetics and calcium reco...

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Bibliographic Details
Main Authors: Yi Chen, Patricia Pais-Roldan, Xuming Chen, Michael H. Frosz, Xin Yu
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10450-3