Increase in excitability of hippocampal neurons during novelty-induced hyperlocomotion in dopamine-deficient mice

Abstract Dopamine is involved in many important brain functions, including voluntary motor movement. Dysfunction of the dopaminergic system can induce motor impairments, including Parkinson’s disease. We previously found that dopamine-deficient (DD) mice became hyperactive in a novel environment 72 ...

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Bibliographic Details
Main Authors: Masayo Fujita, Yukiko Ochiai, Taishi-Clark Takeda, Yoko Hagino, Kazuto Kobayashi, Kazutaka Ikeda
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Molecular Brain
Online Access:http://link.springer.com/article/10.1186/s13041-020-00664-8