Human Cardiac 31P-MR Spectroscopy at 3 Tesla Cannot Detect Failing Myocardial Energy Homeostasis during Exercise

Human Cardiac 31P-MR Spectroscopy at 3 Tesla Cannot Detect Failing Myocardial Energy Homeostasis during Exercise

Phosphorus-31 magnetic resonance spectroscopy (31P-MRS) is a unique non-invasive imaging modality for probing in vivo high-energy phosphate metabolism in the human heart. We investigated whether current 31P-MRS methodology would allow for clinical applications to detect exercise-induced changes in (...

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Bibliographic Details
Main Authors: Adrianus J. Bakermans, Jason N. Bazil, Aart J. Nederveen, Gustav J. Strijkers, S. Matthijs Boekholdt, Daniel A. Beard, Jeroen A. L. Jeneson
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Physiology
Subjects:
myocardial energy metabolism
phosphorus-31 magnetic resonance spectroscopy
computational modeling
cardiac exercise stress testing
hypertrophic cardiomyopathy
energy homeostasis
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00939/full

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http://journal.frontiersin.org/article/10.3389/fphys.2017.00939/full

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