CD8α is expressed by human monocytes and enhances FcγR-dependent responses

<p>Abstract</p> <p>Background</p> <p>CD8α enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8α is also found on dendritic cells and rat macro...

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Bibliographic Details
Main Authors: Ng Marcus CY, Sekar Yokananth, Marcet-Palacios Marcelo, Gibbings Derrick J, Befus A Dean
Format: Article
Language:English
Published: BMC 2007-08-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/8/12