Spatio-temporal mRNA tracking in the early zebrafish embryo

Early stages of embryogenesis are known to depend on subcellular localization and transport of maternal mRNA, but systematic analyses have been hindered by a lack of methods for tracking of RNA. Here the authors combine spatially-resolved transcriptomics and single-cell RNA labeling to perform a spa...

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Bibliographic Details
Main Authors: Karoline Holler, Anika Neuschulz, Philipp Drewe-Boß, Janita Mintcheva, Bastiaan Spanjaard, Roberto Arsiè, Uwe Ohler, Markus Landthaler, Jan Philipp Junker
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23834-1