Safety and efficacy of glibenclamide combined with rtPA in acute cerebral ischemia with occlusion/stenosis of anterior circulation (SE-GRACE): study protocol for a randomized controlled trial

Safety and efficacy of glibenclamide combined with rtPA in acute cerebral ischemia with occlusion/stenosis of anterior circulation (SE-GRACE): study protocol for a randomized controlled trial

Abstract Background Thrombolysis with recombinant tissue plasminogen activator (rtPA) improves outcome for patients with acute ischemic stroke (AIS), but many of them still have substantial disability. Glibenclamide (US adopted name, glyburide), a long-acting sulfonylurea, shows promising result in...

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Bibliographic Details
Main Authors: Kaibin Huang, Zhong Ji, Yongming Wu, Yunqiang Huang, Guangning Li, Saijun Zhou, Zhi Yang, Wenguo Huang, Guoshuai Yang, Guohu Weng, Pingyan Chen, Suyue Pan
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Neurology
Subjects:
Combined treatment
Glibenclamide
Randomized controlled trial
Stroke
Online Access:http://link.springer.com/article/10.1186/s12883-020-01823-z

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http://link.springer.com/article/10.1186/s12883-020-01823-z

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