Mutational Profile and Clonal Evolution of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Mutational Profile and Clonal Evolution of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Primary refractory/relapsed diffuse large B-cell lymphoma (rrDLBCL) is an unresolved issue for DLBCL treatment and new treatments to overcome resistance is required. To explore the genetic mechanisms underlying treatment resistance in rrDLBCL and to identify candidate genes, we performed targeted de...

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Bibliographic Details
Main Authors: Boram Lee, Hyunwoo Lee, Junhun Cho, Sang Eun Yoon, Seok Jin Kim, Woong-Yang Park, Won Seog Kim, Young Hyeh Ko
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
refractory diffuse large B-cell lymphoma
relapsed diffuse large B-cell lymphoma
chemotherapy resistance
tumor evolution
immune evasion
prognostic marker
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.628807/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.628807/full

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