Cellular Metabolomics Profiles Associated With Drug Chemosensitivity in AML

Cellular Metabolomics Profiles Associated With Drug Chemosensitivity in AML

BackgroundAcute myeloid leukemia (AML) is a hematological malignancy with a dismal prognosis. For over four decades, AML has primarily been treated by cytarabine combined with an anthracycline. Although a significant proportion of patients achieve remission with this regimen, roughly 40% of children...

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Bibliographic Details
Main Authors: Bradley Stockard, Neha Bhise, Miyoung Shin, Joy Guingab-Cagmat, Timothy J. Garrett, Stanley Pounds, Jatinder K. Lamba
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
leukemia
AML
drug resistance
cytarabine
doxorubicin
metabolomics
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.678008/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.678008/full

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