GSK-3β and Vitamin D Receptor are Involved in β-Catenin and Snail Signaling in High Glucose-Induced Epithelial-Mesenchymal Transition of Mouse Podocytes

GSK-3β and Vitamin D Receptor are Involved in β-Catenin and Snail Signaling in High Glucose-Induced Epithelial-Mesenchymal Transition of Mouse Podocytes

Background: Epithelial-mesenchymal transition (EMT) is recognized to play an important role in diabetic nephropathy (DN). Objective: To analyze the roles of glycogen synthase kinase 3β (GSK-3β), β-catenin and Snail signaling in high glucose (HG)-induced mouse podocytes EMT. Methods: Differentiated p...

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Bibliographic Details
Main Authors: Jia Guo, Nannan Xia, Lili Yang, Sijie Zhou, Qian Zhang, Yingjin Qiao, Zhangsuo Liu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Podocytes
Epithelial-mesenchymal transition
Glycogen synthase kinase 3β
β-catenin
Snail
Diabetic nephropathy
Online Access:http://www.karger.com/Article/FullText/358678

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http://www.karger.com/Article/FullText/358678

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