HIV Exploits Antiviral Host Innate GCN2-ATF4 Signaling for Establishing Viral Replication Early in Infection

Antiviral innate host defenses against acute viral infections include suppression of host protein synthesis to restrict viral protein production. Less is known about mechanisms by which viral pathogens subvert host antiviral innate responses for establishing their replication and dissemination. We i...

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Bibliographic Details
Main Authors: Guochun Jiang, Clarissa Santos Rocha, Lauren A. Hirao, Erica A. Mendes, Yuyang Tang, George R. Thompson, Joseph K. Wong, Satya Dandekar, Ruth Ruprecht, Vinayaka R. Prasad
Format: Article
Language:English
Published: American Society for Microbiology 2017-05-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/3/e01518-16