Very low oral exposure to prions of brain or saliva origin can transmit chronic wasting disease.

The minimum infectious dose required to induce CWD infection in cervids remains unknown, as does whether peripherally shed prions and/or multiple low dose exposures are important factors in CWD transmission. With the goal of better understand CWD infection in nature, we studied oral exposures of dee...

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Bibliographic Details
Main Authors: Nathaniel D Denkers, Clare E Hoover, Kristen A Davenport, Davin M Henderson, Erin E McNulty, Amy V Nalls, Candace K Mathiason, Edward A Hoover
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0237410