Blockage of CR1 prevents activation of rodent microglia

The importance of the complement system in Alzheimer's disease (AD) pathogenesis has been emphasized through recent genome wide association studies. However, the cellular and molecular role of these complement proteins is not fully understood. Microglia express complement receptors and the acti...

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Bibliographic Details
Main Authors: Helen Crehan, John Hardy, Jennifer Pocock
Format: Article
Language:English
Published: Elsevier 2013-06-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611300065X