Heavy alcohol drinking downregulates ALDH2 gene expression but heavy smoking up-regulates SOD2 gene expression in head and neck squamous cell carcinoma

Heavy alcohol drinking downregulates ALDH2 gene expression but heavy smoking up-regulates SOD2 gene expression in head and neck squamous cell carcinoma

Abstract Background This study aims to determine the relationship between expression levels of ALDH2 and SOD2 genes and clinical parameters such as alcohol drinking, tobacco smoking, primary site of HNSCC, and human papilloma virus (HPV) state. Methods Gene expression data were obtained from gene ex...

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Bibliographic Details
Main Authors: Dong Jin Lee, Hyung Min Lee, Jin Hwan Kim, II Seok Park, Young Soo Rho
Format: Article
Language:English
Published: BMC 2017-08-01
Series:World Journal of Surgical Oncology
Subjects:
Microarray
ALDH2
SOD2
Expression
Alcohol
Smoking
Online Access:http://link.springer.com/article/10.1186/s12957-017-1225-1

Internet

http://link.springer.com/article/10.1186/s12957-017-1225-1

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