Helicobacter hepaticus is required for immune targeting of bacterial heat shock protein 60 and fatal colitis in mice

Helicobacter hepaticus is required for immune targeting of bacterial heat shock protein 60 and fatal colitis in mice

Gut microbiota and the immune system are in constant exchange shaping both host immunity and microbial communities. Here, improper immune regulation can cause inflammatory bowel disease (IBD) and colitis. Antibody therapies blocking signaling through the CD40–CD40L axis showed promising results as t...

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Bibliographic Details
Main Authors: Verena Friedrich, Ignasi Forné, Dana Matzek, Diana Ring, Bastian Popper, Lara Jochum, Stefanie Spriewald, Tobias Straub, Axel Imhof, Anne Krug, Bärbel Stecher, Thomas Brocker
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Gut Microbes
Subjects:
colitis
cd40
helicobacter hepaticus
groel
cd103+ dcs
itregs
Online Access:http://dx.doi.org/10.1080/19490976.2021.1882928

Internet

http://dx.doi.org/10.1080/19490976.2021.1882928

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