Rho Family GTPases in Cancer

Rho GTPases have emerged as pivotal drivers of cancer metastasis in multiple cancer types. Therefore, understanding their dysregulation in cancer and developing drugs to inhibit their activation have become priorities. Even though oncogenic point mutations and splice variants have been reported in a...

Full description

Bibliographic Details
Main Author: Suranganie Dharmawardhane
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
Rho
Rac
Online Access:https://www.mdpi.com/2072-6694/13/6/1271