Primary tumorectomy promotes angiogenesis and pulmonary metastasis in osteosarcoma-bearing nude mice

Primary tumorectomy promotes angiogenesis and pulmonary metastasis in osteosarcoma-bearing nude mice

PURPOSE: To investigate the effect of primary tumorectomy on angiogenesis and pulmonary metastasis in osteosarcoma-bearing nude mice. METHODS: Osteosarcoma was introduced to nude mice via subcutaneous injection of MG-63 cells. One hundred and eighty osteosarcoma-bearing mice were used equally in 3 p...

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Bibliographic Details
Main Authors: Zhi-Yuan Wang, Jiong Mei, You-Shui Gao, Ming Ni, Bin Yao
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2013-03-01
Series:Acta Cirurgica Brasileira
Subjects:
Osteosarcoma
Neplasm Metastasis
Vascular Endothelial Growth Factor A
Endostatins
Tumor Resistance
Mice
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000300006

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000300006

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