Highly Stereoselective Synthesis of a Compound Collection Based on the Bicyclic Scaffolds of Natural Products

Highly Stereoselective Synthesis of a Compound Collection Based on the Bicyclic Scaffolds of Natural Products

Despite the great contribution of natural products in the history of successful drug discovery, there are significant limitations that persuade the pharmaceutical industry to evade natural products in drug discovery research. The extreme scarcity as well as structural complexity of natural products...

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Bibliographic Details
Main Authors: Murali Annamalai, Stanimira Hristeva, Martyna Bielska, Raquel Ortega, Kamal Kumar
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:Molecules
Subjects:
natural products
drug discovery
scaffolds
Aza-heterocycles
European Lead Factory
Online Access:http://www.mdpi.com/1420-3049/22/5/827

Internet

http://www.mdpi.com/1420-3049/22/5/827

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