Optimized generation of high-resolution phantom images using cGAN: Application to quantification of Ki67 breast cancer images.

In pathology, Immunohistochemical staining (IHC) of tissue sections is regularly used to diagnose and grade malignant tumors. Typically, IHC stain interpretation is rendered by a trained pathologist using a manual method, which consists of counting each positively- and negatively-stained cell under...

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Bibliographic Details
Main Authors: Caglar Senaras, Muhammad Khalid Khan Niazi, Berkman Sahiner, Michael P Pennell, Gary Tozbikian, Gerard Lozanski, Metin N Gurcan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5942823?pdf=render