Considering Abundance, Affinity, and Binding Site Availability in the NF-κB Target Selection Puzzle

Considering Abundance, Affinity, and Binding Site Availability in the NF-κB Target Selection Puzzle

The NF-κB transcription regulation system governs a diverse set of responses to various cytokine stimuli. With tools from in vitro biochemical characterizations, to omics-based whole genome investigations, great strides have been made in understanding how NF-κB transcription factors control the expr...

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Bibliographic Details
Main Authors: Ruth Brignall, Amy T. Moody, Shibin Mathew, Suzanne Gaudet
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
NF-κB
transcription regulation
specificity
accessibility
competition
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00609/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00609/full

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