A picorna-like virus suppresses the N-end rule pathway to inhibit apoptosis
The N-end rule pathway is an evolutionarily conserved proteolytic system that degrades proteins containing N-terminal degradation signals called N-degrons, and has emerged as a key regulator of various processes. Viruses manipulate diverse host pathways to facilitate viral replication and evade anti...
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-12-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/30590 |