A picorna-like virus suppresses the N-end rule pathway to inhibit apoptosis

The N-end rule pathway is an evolutionarily conserved proteolytic system that degrades proteins containing N-terminal degradation signals called N-degrons, and has emerged as a key regulator of various processes. Viruses manipulate diverse host pathways to facilitate viral replication and evade anti...

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Bibliographic Details
Main Authors: Zhaowei Wang, Xiaoling Xia, Xueli Yang, Xueyi Zhang, Yongxiang Liu, Di Wu, Yuan Fang, Yujie Liu, Jiuyue Xu, Yang Qiu, Xi Zhou
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/30590