Meta-analysis identifies gene-by-environment interactions as demonstrated in a study of 4,965 mice.

Identifying environmentally-specific genetic effects is a key challenge in understanding the structure of complex traits. Model organisms play a crucial role in the identification of such gene-by-environment interactions, as a result of the unique ability to observe genetically similar individuals a...

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Bibliographic Details
Main Authors: Eun Yong Kang, Buhm Han, Nicholas Furlotte, Jong Wha J Joo, Diana Shih, Richard C Davis, Aldons J Lusis, Eleazar Eskin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3886926?pdf=render