The triterpenoid CDDO-Me inhibits bleomycin-induced lung inflammation and fibrosis.

Pulmonary Fibrosis (PF) is a devastating progressive disease in which normal lung structure and function is compromised by scarring. Lung fibrosis can be caused by thoracic radiation, injury from chemotherapy and systemic diseases such as rheumatoid arthritis that involve inflammatory responses. CDD...

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Bibliographic Details
Main Authors: Ajit A Kulkarni, Thomas H Thatcher, Hsi-Min Hsiao, Keith C Olsen, Robert Matthew Kottmann, Jason Morrissette, Terry W Wright, Richard P Phipps, Patricia J Sime
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3669327?pdf=render