Differential structural remodelling of heparan sulfate by chemokines: the role of chemokine oligomerization

Chemokines control the migration of cells in normal physiological processes and in the context of disease such as inflammation, autoimmunity and cancer. Two major interactions are involved: (i) binding of chemokines to chemokine receptors, which activates the cellular machinery required for movement...

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Bibliographic Details
Main Authors: Douglas P. Dyer, Elisa Migliorini, Catherina L. Salanga, Dhruv Thakar, Tracy M. Handel, Ralf P. Richter
Format: Article
Language:English
Published: The Royal Society 2017-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160286