Predicting progression and cognitive decline in amyloid-positive patients with Alzheimer’s disease

Predicting progression and cognitive decline in amyloid-positive patients with Alzheimer’s disease

Abstract Background In Alzheimer’s disease, amyloid- β (A β) peptides aggregate in the lowering CSF amyloid levels - a key pathological hallmark of the disease. However, lowered CSF amyloid levels may also be present in cognitively unimpaired elderly individuals. Therefore, it is of great value to e...

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Bibliographic Details
Main Authors: Hákon Valur Dansson, Lena Stempfle, Hildur Egilsdóttir, Alexander Schliep, Erik Portelius, Kaj Blennow, Henrik Zetterberg, Fredrik D. Johansson, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Amyloid-beta
Progression
Prediction
Machine learning
Online Access:https://doi.org/10.1186/s13195-021-00886-5

Internet

https://doi.org/10.1186/s13195-021-00886-5

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