No detectable effect of a type 2 diabetes-associated TCF7L2 genotype on the incretin effect

No detectable effect of a type 2 diabetes-associated TCF7L2 genotype on the incretin effect

The T allele of TCF7L2 rs7903146 is a common genetic variant associated with type 2 diabetes (T2D), possibly by modulation of incretin action. In this study, we evaluated the effect of the TCF7L2 rs7903146 T allele on the incretin effect and other glucometabol ic parameters in normal glucose toleran...

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Bibliographic Details
Main Authors: David S Mathiesen, Jonatan I Bagger, Katrine B Hansen, Anders E Junker, Astrid Plamboeck, Signe Harring, Thomas Idorn, Mads Hornum, Jens J Holst, Anna E Jonsson, Torben Hansen, Tina Vilsbøll, Asger Lund, Filip K Knop
Format: Article
Language:English
Published: Bioscientifica 2020-12-01
Series:Endocrine Connections
Subjects:
tcf7l2
transcription factor 7-like 2
snp
incretin effect
incretins
type 2 diabetes
Online Access:https://ec.bioscientifica.com/view/journals/ec/9/12/EC-20-0471.xml

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https://ec.bioscientifica.com/view/journals/ec/9/12/EC-20-0471.xml

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