Broad Bactericidal Activity of the <i>Myoviridae</i> Bacteriophage Lysins LysAm24, LysECD7, and LysSi3 against Gram-Negative ESKAPE Pathogens

Broad Bactericidal Activity of the <i>Myoviridae</i> Bacteriophage Lysins LysAm24, LysECD7, and LysSi3 against Gram-Negative ESKAPE Pathogens

The extremely rapid spread of multiple-antibiotic resistance among Gram-negative pathogens threatens to move humankind into the so-called &#8220;post-antibiotic era&#8222; in which the most efficient and safe antibiotics will not work. Bacteriophage lysins represent promising alternatives to...

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Bibliographic Details
Main Authors: Nataliia P. Antonova, Daria V. Vasina, Anastasiya M. Lendel, Evgeny V. Usachev, Valentine V. Makarov, Alexander L. Gintsburg, Artem P. Tkachuk, Vladimir A. Gushchin
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Viruses
Subjects:
bacteriophages
<i>Myoviridae</i>
bacteriophage-derived lytic enzyme
enzybiotics
endolysin
in vitro activity
ESKAPE
Online Access:https://www.mdpi.com/1999-4915/11/3/284

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https://www.mdpi.com/1999-4915/11/3/284

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