Transducin-Like Enhancer of Split-1 Inhibits Malignant Behaviors in vitro and Predicts a Better Prognosis in Pancreatic Ductal Adenocarcinoma

Transducin-Like Enhancer of Split-1 Inhibits Malignant Behaviors in vitro and Predicts a Better Prognosis in Pancreatic Ductal Adenocarcinoma

Background: Transducin-like enhancer of split-1 (TLE1), a member of the Groucho/TLE family of transcriptional corepressors, has been reported to be involved in the tumorigenesis of various cancers and function as a clinical prognostic indicator. However, the mechanisms and prognostic significance of...

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Bibliographic Details
Main Authors: Yizhi Wang, Da Yuan, Li Zhou, Zhiyong Liang, Weixun Zhou, Jun Lu, Bolun Jiang, Lei You, Junchao Guo, Yu-Pei Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Oncology
Subjects:
pancreatic ductal adenocarcinoma
transducin-like enhancer of split-1
prognosis
survival
biomarker
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00576/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.00576/full

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