Sex-Specific Anxiety and Prefrontal Cortex Glutamatergic Dysregulation Are Long-Term Consequences of Pre-and Postnatal Exposure to Hypercaloric Diet in a Rat Model

Sex-Specific Anxiety and Prefrontal Cortex Glutamatergic Dysregulation Are Long-Term Consequences of Pre-and Postnatal Exposure to Hypercaloric Diet in a Rat Model

Both maternal and early life malnutrition can cause long-term behavioral changes in the offspring, which depends on the caloric availability and the timing of the exposure. Here we investigated in a rat model whether a high-caloric palatable diet given to the mother and/or to the offspring during th...

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Bibliographic Details
Main Authors: Patricia Rivera, Rubén Tovar, María Teresa Ramírez-López, Juan Antonio Navarro, Antonio Vargas, Juan Suárez, Fernando Rodríguez de Fonseca
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Nutrients
Subjects:
perinatal programming
prefrontal cortex
endocannabinoid system
Online Access:https://www.mdpi.com/2072-6643/12/6/1829

Internet

https://www.mdpi.com/2072-6643/12/6/1829

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