Pivoting of microtubules driven by minus-end-directed motors leads to spindle assembly

Pivoting of microtubules driven by minus-end-directed motors leads to spindle assembly

Abstract Background At the beginning of mitosis, the cell forms a spindle made of microtubules and associated proteins to segregate chromosomes. An important part of spindle architecture is a set of antiparallel microtubule bundles connecting the spindle poles. A key question is how microtubules ext...

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Bibliographic Details
Main Authors: Lora Winters, Ivana Ban, Marcel Prelogović, Iana Kalinina, Nenad Pavin, Iva M. Tolić
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Biology
Subjects:
Mitotic spindle
Mitosis
Spindle assembly
Antiparallel microtubule bundles
Overlap bundles
Microtubule rotation
Online Access:http://link.springer.com/article/10.1186/s12915-019-0656-2

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http://link.springer.com/article/10.1186/s12915-019-0656-2

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