Genetic engineering of Escherichia coli to improve L-phenylalanine production

Genetic engineering of Escherichia coli to improve L-phenylalanine production

Abstract Background L-phenylalanine (L-Phe) is an essential amino acid for mammals and applications expand into human health and nutritional products. In this study, a system level engineering was conducted to enhance L-Phe biosynthesis in Escherichia coli. Results We inactivated the PTS system and...

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Bibliographic Details
Main Authors: Yongfei Liu, Yiran Xu, Dongqin Ding, Jianping Wen, Beiwei Zhu, Dawei Zhang
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Biotechnology
Subjects:
L-phenylalanine
Metabolic engineering
Proteomics
TyrR
AroD
Online Access:http://link.springer.com/article/10.1186/s12896-018-0418-1

Internet

http://link.springer.com/article/10.1186/s12896-018-0418-1

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