Genetic polymorphisms of the main transcription factors for adiponectin gene promoter in regulation of adiponectin levels: association analysis in three European cohorts.

Genetic polymorphisms of the main transcription factors for adiponectin gene promoter in regulation of adiponectin levels: association analysis in three European cohorts.

Adiponectin serum concentrations are an important biomarker in cardiovascular epidemiology with heritability etimates of 30-70%. However, known genetic variants in the adiponectin gene locus (ADIPOQ) account for only 2%-8% of its variance. As transcription factors are thought to play an under-acknow...

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Bibliographic Details
Main Authors: Lyudmyla Kedenko, Claudia Lamina, Tobias Kiesslich, Karen Kapur, Sven Bergmann, Dawn Waterworth, Iris M Heid, H-Erich Wichmann, Igor Kedenko, Florian Kronenberg, Bernhard Paulweber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3528683?pdf=render

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http://europepmc.org/articles/PMC3528683?pdf=render

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