Tissue Engineering Using Vascular Organoids From Human Pluripotent Stem Cell Derived Mural Cell Phenotypes

Tissue Engineering Using Vascular Organoids From Human Pluripotent Stem Cell Derived Mural Cell Phenotypes

Diffusion is a limiting factor in regenerating large tissues (100–200 μm) due to reduced nutrient supply and waste removal leading to low viability of the regenerating cells as neovascularization of the implant by the host is a slow process. Thus, generating prevascularized tissue engineered constru...

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Bibliographic Details
Main Authors: Maria Markou, Dimitrios Kouroupis, Fotios Badounas, Athanasios Katsouras, Athena Kyrkou, Theodore Fotsis, Carol Murphy, Eleni Bagli
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
mural cells
tissue engineering
induced pluripotent stem cells
smooth muscle cells
vascularization
vascular organoids
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00278/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00278/full

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