Prenatal S-Adenosine Methionine (SAMe) Induces Changes in Gene Expression in the Brain of Newborn Mice That Are Prevented by Co-Administration of Valproic Acid (VPA)

In previous studies, we produced changes in gene expression in the brain of mice by early postnatal administration of valproic acid (VPA), with distinct differences between genders. The addition of S-adenosine methionine (SAMe) normalized the expression of most genes in both genders, while SAMe alon...

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Bibliographic Details
Main Authors: Liza Weinstein-Fudim, Zivanit Ergaz, Moshe Szyf, Asher Ornoy
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
ASD
VPA
Online Access:https://www.mdpi.com/1422-0067/21/8/2834