MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes

<p>Abstract</p> <p>Background</p> <p>The binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitopes has potential applications in vaccine design and in better unde...

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Bibliographic Details
Main Authors: Mittelmann Hans D, Bordner Andrew J
Format: Article
Language:English
Published: BMC 2010-09-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/482