Consequences of PPARα Invalidation on Glutathione Synthesis: Interactions with Dietary Fatty Acids
Glutathione (GSH) derives from cysteine and plays a key role in redox status. GSH synthesis is determined mainly by cysteine availability and γ-glutamate cysteine ligase (γGCL) activity. Because PPARα activation is known to control the metabolism of certain amino acids, GSH synthesis from cysteine a...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2011-01-01
|
| Series: | PPAR Research |
| Online Access: | http://dx.doi.org/10.1155/2011/256186 |