Retrotransposon silencing by DNA methylation can drive mammalian genomic imprinting.
Among mammals, only eutherians and marsupials are viviparous and have genomic imprinting that leads to parent-of-origin-specific differential gene expression. We used comparative analysis to investigate the origin of genomic imprinting in mammals. PEG10 (paternally expressed 10) is a retrotransposon...
Main Authors: | , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-04-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC1851980?pdf=render |