A high-light sensitivity optical neural silencer: development, and application to optogenetic control of nonhuman primate cortex

Technologies for silencing the electrical activity of genetically-targeted neurons in the brain are important for assessing the contribution of specific cell types and pathways towards behaviors and pathologies. Recently we found that archaerhodopsin-3 from Halorubrum sodomense (Arch), a light-driv...

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Bibliographic Details
Main Authors: Xue eHan, Brian Y Chow, Huihui eZhou, Nathan C Klapoetke, Amy eChuong, Reza eRajimehr, Aimei eYang, Michael V Baratta, Jonathan eWinkle, Robert eDesimone, Edward S Boyden
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-04-01
Series:Frontiers in Systems Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2011.00018/full